FlySketchDraw, highlight, everywhere. Read about it and download from the FlySketch website.
FlyGestureMouse gestures made easy.
FlyGesture comes with actions to type text, call command keys, open files or folders, open websites, run Automator workflows, run custom AppleScript, and various other commands- all just by moving your mouse around in a little grid. Watch a movie that demonstrates creating and using a new gesture to open Safari.
Download version 1.0.2, requires Mac OS X v. 10.4.3 or later.
Programmer's StuffFM is a big fan of open source software, and we even like to give some back every once in a while.
FMDB, an easy Cocoa wrapper around SQLite.